http://manhattan.sourceforge.net/

The Manhattan Virtual Classroom is a fast, stable and effective course management system that runs on Linux and other Unix-like systems. It's written entirely in the C programming language (fast! - light hardware requirements) and is 100% database-free (no MySQL administration, no tuning issues- simple!) Manhattan supports thousands of users at its Western New England College home, and at other colleges and schools around the world. The software is licensed under the General Public License.